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Liver Cancer


Introduction:

Liver cancer is a broad terminology for various cancers that occur in the liver. The cause of each variety of liver cancer is multifold

For example, the primary hepatocellular carcinoma or HCC is usually in a diseased liver background. The liver could be diseased due to Diabetes/Metabolic syndrome induced by steatohepatitis (Fatty changes with inflammation in the liver), alcohol, hepatitis B or C, or various other reasons.


Types:

Hepatocellular carcinoma

Cholangiocarcinoma

Metastasis: Colorectal metastases, Neuroendocrine tumour metastases, Metastases from cancers of the breast, oesophagus, lungs, and other organs


Diagnosis:

Good imaging: PETCT scan, MRI/MRCP

Blood tests, Serum AFP, CA19-9, CEA


Treatment:

Single: Surgery/ Ablation/ Embolization

Multiple: Embolization/ Chemotherapy/ Surgery if limited to one lobe

Oligo (1-2 tumours): Ablation/ Surgery/ Embolization


Localised treatment is either preceded or followed by systemic treatment in the form of Chemotherapy, Immunotherapy, targeted therapy/biological


The order of the treatment is best chosen after a discussion with all the cancer specialists in the panel


Follow up:

PET CT scan after 3 months after completion of treatment or earlier based on the clinical scenario

Further tumor markers and clinical examination followed by scans will be performed every 3-6 months


Regular follow up and timely intervention is important


Videos:

Liver resection

Microwave ablation

Embolization

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